Madonna has been discharged from hospital and is home and feeling better after an intensive care stay, the BBC understands.
News of her ill health was shared by her manager, who said she had suffered a "serious bacterial infection".
The 64-year-old was due to begin a seven-month world tour in the coming weeks, but has had to postpone it.
She was taken to her New York home in a private ambulance, a source told CNN, adding: "She's in the clear."
It is not clear what initially caused Madonna's infection, but doctors said it became extremely serious and required treatment in intensive care.
Infections can develop into a life-threatening condition called sepsis or blood poisoning.
Madonna, who is very private about health matters, was in the final stages of rehearsals ahead of her extensive world tour.
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